osteoclast precursor

RNAKL induce osteoclast differentiation and function by binding to its receptor RANK (receptor activator of NF- κ B) on the osteoclast precursor and mature osteoclast.
RANKL与破骨细胞表面的RANK(receptoractivator of NF-κB，核激活因子受体)结合后，刺激破骨细胞前体细胞向成熟破骨细胞分化，也刺激了成熟破骨细胞发挥骨吸收功能。