iron homeostasis

基本解释

AIM To explore whether there is relationship between iron homeostasis disorder and neurodegeneration induced by aluminum(Al) overload.
目的探讨铝致神经元退行性变是否与脑铁代谢失衡有关。
CONCLUSION Al overload may interfere with brain iron homeostasis, which may be responsible for neurodegeneration induced by Al toxicity.
结论铝过负荷致神经元退变可能与其干扰脑铁代谢有关。
CONCLUSION: Nimodipine relieves the neurodegeneration induced by aluminum overload through inhibiting the expression of HO-1 and keeping the homeostasis of iron.
结论：尼莫地平可能通过抑制HO-1表达、维持铁离子稳态，减轻铝过负荷所致的神经元退行性变。